Three swastikas were spray painted inside a Jewish fraternity, Alpha Epsilon Pi, house at Vanderbilt University, Israel Hayom reports.
AEPi International executive director Andrew Borans linked the incident to a "rising tide of anti-Semitism."
An investigation has been launched into the incident.
The local newspaper, The Tennessean, cited a statement that Provost Susan R. Wente sent to students Monday reporting that the graffiti had been found Saturday after a party at the Alpha Epsilon Pi house.
Wente condemned use of the symbol, which she said is "associated with hate, anti-Semitism, violence, death, and murder."
She said anyone with information about the swastikas should call Vanderbilt police.
Vanderbilt officials, according to The Tennessean, believe the vandalism took place between 1:55 and 3:22 a.m. Saturday. Vanderbilt police said investigators were still doing interviews and have yet to identify any suspects.